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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
30/12/2016 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
SEPÚLVEDA, R V.; VALENTE, F. L.; REIS, E. C. C.; ARAÚJO, F. R.; ELEOTÉRIO R. B.; QUEIROZ, P. V. S.; BORGES, A. P. B. |
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Afiliação: |
RODRIGO V. SEPÚLVEDA, UFV; FABRÍCIO L. VALENTE, UFV; EMILY C. C. REIS, UFV; FABIANA R ARAÚJO, UFV; RENATO B. ELEOTÉRIO, UFV; PAULO V. S. QUEIROZ, UFV; ANDRÉA P. B. BORGES, UFV. |
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Título: |
Bacterial cellulose and bacterial cellulose/polycaprolactone composites as tissue substitutes in rabbits' cornea. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 10, p. 986-992, out. 2016. |
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Idioma: |
Inglês |
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Conteúdo: |
In order to test the performance of bacterial cellulose/polycaprolactone composite (BC/PCL) and pure bacterial cellulose (BC) as tissue substitutes in rabbits? cornea, a superficial ulcer containing 5mm in diameter and 0.2mm deep was made in the right cornea of 36 rabbits, then a interlayer pocket was created from the basis of this ulcer. Twelve rabbits received BC/PCL membrane and 12 were treated with BC membranes, both membranes with 8mm in diameter. The remaining rabbits received no membrane constituting the control group. The animals were clinically followed up for 45 days. Three animals of each group were euthanized at three, seven, 21, and 45 days after implantation for histological examination of the cornea along with the implant. Clinical observation revealed signs of moderate inflammatory process, decreasing from day 20th in the implanted groups. Histology showed absence of epithelium on the membranes, fibroplasia close to the implants, lymph inflammatory infiltrate with giant cells, collagen disorganization, with a predominance of immature collagen fibers in both groups with implants. Although inflammatory response is acceptable, the membranes used does not satisfactorily played the role of tissue substitute for the cornea during the study period. |
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Palavras-Chave: |
Bacterial cellulose; Bacterial cellulose/polycaprolactone composite; Biomaterial; Celulose bacteriana; Corneal ulcer; Engenharia de tecido; Modelo animal; Tissue substitutes; Úlcera de córnea. |
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Thesagro: |
Coelho. |
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Thesaurus Nal: |
Animal models; Biocompatible materials; Cornea; Gluconacetobacter xylinus; Rabbits; Tissue engineering. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/152581/1/Bacterial-cellulose-and-bacterial.pdf
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Marc: |
LEADER 02466naa a2200385 a 4500
001 2059677
005 2017-12-29
008 2016 bl uuuu u00u1 u #d
100 1 $aSEPÚLVEDA, R V.
245 $aBacterial cellulose and bacterial cellulose/polycaprolactone composites as tissue substitutes in rabbits' cornea.$h[electronic resource]
260 $c2016
520 $aIn order to test the performance of bacterial cellulose/polycaprolactone composite (BC/PCL) and pure bacterial cellulose (BC) as tissue substitutes in rabbits? cornea, a superficial ulcer containing 5mm in diameter and 0.2mm deep was made in the right cornea of 36 rabbits, then a interlayer pocket was created from the basis of this ulcer. Twelve rabbits received BC/PCL membrane and 12 were treated with BC membranes, both membranes with 8mm in diameter. The remaining rabbits received no membrane constituting the control group. The animals were clinically followed up for 45 days. Three animals of each group were euthanized at three, seven, 21, and 45 days after implantation for histological examination of the cornea along with the implant. Clinical observation revealed signs of moderate inflammatory process, decreasing from day 20th in the implanted groups. Histology showed absence of epithelium on the membranes, fibroplasia close to the implants, lymph inflammatory infiltrate with giant cells, collagen disorganization, with a predominance of immature collagen fibers in both groups with implants. Although inflammatory response is acceptable, the membranes used does not satisfactorily played the role of tissue substitute for the cornea during the study period.
650 $aAnimal models
650 $aBiocompatible materials
650 $aCornea
650 $aGluconacetobacter xylinus
650 $aRabbits
650 $aTissue engineering
650 $aCoelho
653 $aBacterial cellulose
653 $aBacterial cellulose/polycaprolactone composite
653 $aBiomaterial
653 $aCelulose bacteriana
653 $aCorneal ulcer
653 $aEngenharia de tecido
653 $aModelo animal
653 $aTissue substitutes
653 $aÚlcera de córnea
700 1 $aVALENTE, F. L.
700 1 $aREIS, E. C. C.
700 1 $aARAÚJO, F. R.
700 1 $aELEOTÉRIO R. B.
700 1 $aQUEIROZ, P. V. S.
700 1 $aBORGES, A. P. B.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 36, n. 10, p. 986-992, out. 2016.
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Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
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| Registros recuperados : 4 | |
| 2. |  | ELEOTÉRIO, R. B.; SEPÚLVEDA, R. V.; REIS, E. C. C.; VALENTE, F. L.; BORGES, A P. B. Isolation, expansion and differentiation of mesenchymal stromal cells from rabbits' marrow'. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 5, p. 423-430, maio. 2016.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 3. | | SEPÚLVEDA, R V.; VALENTE, F. L.; REIS, E. C. C.; ARAÚJO, F. R.; ELEOTÉRIO R. B.; QUEIROZ, P. V. S.; BORGES, A. P. B. Bacterial cellulose and bacterial cellulose/polycaprolactone composites as tissue substitutes in rabbits' cornea. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 10, p. 986-992, out. 2016.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 4. | | MURTA, A. R.; ABREU JUNIOR, N. B.; OLIVEIRA, L. S.; REIS, E. C. C.; VALENTE, F. L.; GONÇALVES, G. P.; ELEOTÉRIO, R. B.; BORGES, A. P. B. Perfil epidemiológico e análise microbiológica da infecção de sítio cirúrgico em pacientes humanos e animais de companhia. Pesquisa Veterinária Brasileira v. 35, n.7, p. 652-658, julho 2015.| Biblioteca(s): Embrapa Unidades Centrais. |
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| Registros recuperados : 4 | |
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